General Cell Lines and Cell Cultures
ATCC Human rhinovirus 17; RNA; Strain: 33342
Genomic RNA isolated from H1 HeLa cells (ATCC CRL-1958) infected with Human rhinovirus 17 strain 33342 (ATCC VR-1663). This product was prepared using methods known to inactivate viruses. It is suitable for use in RT-PCR or other RNA-based procedures. The source organism and host cells are also available through the ATCC catalog.
Eurofins Discoverx PrecisION hKv7.4 Recombinant Stable Cell Line, 2 vials. (CYL3092)
The PrecisION hKv7.4 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv7.4 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv7.4 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Lonza Walkersville Hu Melanocyte - Neo Nufe Kit
The Nucleofector 2b Device (or older generations I or II) works with cell type specific kits each of them dedicated to an individual primary cell This Nucleofector Kit is the optimal kit for efficient transfectiion of primary human melanocytes The respective cell type-specific Optimized Protocol or recommendation is available under Instructions or in our Lonza Bioscience knowledge database In this Optimized Protocol the best Nucleofection conditions are indicated In addition we share our experience and knowledge for treatment of this cell type
Eurofins Discoverx ChemiBrite GPR120 Receptor Stable Cell Line, 2 vials. (HTS225L)
The ChemiBrite GPR120 Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. free fatty acids) based activation of FFAR4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FFAR4, a naturally Gq coupled GPCR. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of FFAR4, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Biochain Institute Inc Frozen Tissue Section - Human Diabetic Diseased Tissue: Small Intestine: Ileum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter U2OS IL5RA/CSF2RB Dimerization Cell Line, 2 vials. (93-0972C3)
The PathHunter IL5RA/CSF2RB Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-5) induced dimerization of IL5RA/CSF2RB receptors. This product uses EFC technology. The cell line included overexpresses CSF2RB target protein fused to PK alongside IL5RA target protein fused to EA. Upon ligand-induced dimerization of IL5RA/CSF2RB, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/interleukins.
Eurofins Discoverx PrecisION hGABAA α5/β3/γ2 Recombinant Stable Cell Line, 2 vials. (CYL3073)
The PrecisION hGABAA α5/β3/γ2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying GABAA α5/β3/γ2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses GABAA α5/β3/γ2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Biochain Institute Inc Paraffin Tissue Section Panel - Human Disease Tissue, Alzheimer's Disease, Multi-tissue II, 7 different tissues, 5 slides/PK
BioChain's FFPE Alzheimer's diseased brain tissue panels are designed for rapidly screening Alzheimer's disease-specific genes or proteins in brain tissues. Tissues are arrayed on positively charged glass slides. Alzheimer's diseased brain tissues on T8236444Alz are selected based on functional regions, while those on T8236445Alz are selected based on anatomical regions. T8236564Alz contains both functional and anatomical regions of Alzheimer's diseased brain tissues. Normal brain tissue panels are also available in the identical format as controls. T8236446Alz contains both Alzheimer's diseased brain tissues and normal brain tissues.
ATCC Legionella anisa; Strain WA-316-C3; genomic DNA
Genomic DNA isolated from Legionella anisa strain WA-316-C3. This bacterial strain is also available as ATCC Catalog No. 35292™.
Eurofins Discoverx ChemiScreen H1 Histamine Receptor Membrane Preparation, 1 vial. (HTS050M)
The ChemiScreen H1 Histamine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of HRH1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen α1B Adrenergic Receptor Stable Cell Line, 2 vials. (HTS158C)
The ChemiScreen α1B Adrenergic Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. epinephrine and norepinephrine) based activation of ADRA1B GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses ADRA1B alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of ADRA1B, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Schaalia odontolytica; genomic DNA
Genomic DNA isolated from Schaalia odontolytica strain NCTC 9931. This bacterial strain is also available as ATCC Catalog No.: 17982™.
ATCC Aspergillus niger
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.